Publications

"D-amino acids govern stationary phase cell wall remodeling in bacteria", Lam, H.; Oh, D.C.; Cava, F.; Takacs, C.N.; Clardy, J.; de Pedro, M.A.; Waldor, M.K. Science. 2009, 325, (5947), 1552-5. Pubmed Link

 

"Synthesis and in vitro DMPK profiling of a 1,2-dioxolane-based library with activity against Plasmodium falciparum", Martyn, D.C.; Beletsky, G.; Cortese, J.F.; Tyndall, E.; Liu, H.; Fitzgerald, M.M.; O'Shea, T.J.; Liang, B.; Clardy, J. Bioorg Med Chem Lett. 2009, 19, (19), 5657-60. Pubmed Link

 

"FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases", Mojsilovic-Petrovic, J.; Nedelsky, N.; Boccitto, M.; Mano, I.; Georgiades, S.N.; Zhou, W.; Liu, Y.; Neve, R.L.; Taylor, J.P.; Driscoll, M.; Clardy, J.; Merry, D.; Kalb, R.G. J Neurosci. 2009, 29, (25), 8236-47. Pubmed Link

 

"An indole-containing dauer pheromone component with unusual dauer inhibitory activity at higher concentrations", Butcher, R.A.; Ragains, J.R.; Clardy, J. Org Lett. 2009, 11, (14), 3100-3. Pubmed Link

 

"A stabilized demethoxyviridin derivative inhibits PI3 kinase", Yuan, H.; Pupo, M.T.; Blois, J.; Smith, A.; Weissleder, R.; Clardy, J.; Josephson, L. Bioorg Med Chem Lett. 2009, 19, (15), 4223-7. Pubmed Link

 

"The natural history of antibiotics", Clardy, J.; Fischbach, M.A.; Currie, C.R. Curr Biol. 2009, 19, (11), 437-41. Pubmed Link

 

"A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans", Macosko, E.Z.; Pokala, N.; Feinber, E.H.; Chalasani, S.H.; Butcher, R.A.; Clardy, J.; Bargmann, C.I. Nature. 2009, 458, (7242), 1171-5. Pubmed Link

 

"Dentigerumycin: a bacterial mediator of an ant-fungus symbiosis", Oh, D.C.; Poulsen, M.; Currie, C.R.; Clardy, J. Nat Chem Biol. 2009, 5, (6), 391-3. Pubmed Link

 

"Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum", Patel, V.; Mazitschek, R.; Coleman, B.; Nguyen, C.; Urgaonkar, S.; Cortese, J.; Barker, R.H.; Greenberg, E.; Tang, W.; Bradner, J.E.; Schreiber, S.L.; Duraisingh, M.T.; Wirth, D.F.; Clardy, J. J Med Chem. 2009, 52, (8), 2185-7. Pubmed Link

 

"A colorimetric high-throughput screen for the detection of heme crystallization inhibitors", Rush, M.A.; Baniecki, M.L.; Mazitschek, R.; Cortese, J.F.; Wiegand, R.; Clardy, J.; Wirth, D.F. Antimicrob Agents Chemother. 2009, 53, (6), 2564-8. Pubmed Link

 

"Progestins activate the AKT pathway in leiomyoma cells and promote survival", Hoekstra, A.V.; Sefton, E.C.; Berry, E.; Lu, Z.; Hardt, J.; Marsh, E.; Yin, P.; Clardy, J.; Chakravarti, D.; Bulun, S.; Kim, J.J. J Clin Endocrinol Metab. 2009, 94, (5), 1768-74. Pubmed Link

 

"Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin", Wieland Brown, L.C.; Acker, M.G.; Clardy, J.; Walsh, C.T.; Fischbach, M.A. Proc Natl Acad Sci USA. 2009, 106, (8), 2549-53. Pubmed Link

 

"Biosynthesis of the Caenorhabditis elegans dauer pheromone", Butcher, R.A.; Ragains, J.R.; Li, W.; Ruvkun, G.; Clardy, J.; Mak, H.Y. Proc Natl Acad Sci USA. 2009, 106, (6), 1875-9. Pubmed Link

 

"Mycangimycin, a polyene peroxide from a mutualist Streptomyces sp.", Oh, D.C.; Scott, J.J.; Currie, C.R.; Clardy, J. Org Lett. 2009, 11, (3), 633-6. Pubmed Link

 

"Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors", Dong, C.K.; Patel, V.; Yang, J.C.; Dvorin, J.D.; Duraisingh, M.T.; Clardy, J.; Wirth, D.F. Bioorg Med Chem Lett. 2009, 19, (3), 972-5.  Pubmed Link

 

"Induction of apoptosis in endometrial cancer cells by psammaplysene A involves FOXO1", Berry, E.; Hardt, J.L.; Clardy, J.; Lurain, J.R.; Kim, J.J. Gynecol Oncol. 2009, 112, (2), 331-6. Pubmed Link

 

"Synthesis of spiro-1,2-dioxolanes and their activity against Plasmodium falciparum", Martyn, D.C.; Ramirez, A.P.; Beattie, M.J.; Cortese, J.F.; Patel, V.; Rush, M.A.; Woerpel, K.A.; Clardy, J. Bioorg Med Chem Lett. 2008, 18, (24), 6521-4. Pubmed Link

 

"Actin-aggregating cucurbitacins from Physocarpus capitatus", Maloney, K.N.; Fujita, M.; Eggert, U.S.; Schroeder, F.C.; Field, C.M.; Mitchison, T.J.; Clardy, J. J Nat Prod. 2008, Oct 30, epub ahead of print. Pubmed Link

 

"FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells", Fernandez de Mattos, S.; Villalonga, P.; Clardy, J.; Lam, E.W. Mol Cancer Ther. 2008, 7, (10), 3237-46. Pubmed Link

 

"Identification and characterization of small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase", Patel, V.; Booker, M.; Kramer, M.; Ross, L.; Celatka, C.A.; Kennedy, L.M.; Dvorin, J.D.; Duraisingh, M.T.; Sliz, P.; Wirth, D.F.; Clardy, J. J Biol Chem. 2008, 283, (50), 35078-85. Pubmed Link

 

"Bacterial protection of beetle-fungus mutualism", Scott, J.J.; Oh, D.C.; Yuceer, M.C.; Klepzig, K.D.; Clardy, J.; Currie, C.R. Science. 2008, 322, (5898), 63. Pubmed Link

 

"A potent dauer pheromone component in Caenorhabditis elegans that acts synergistically with other components", Butcher, R.A.; Ragains, J.R.; Kim, E.; Clardy, J. Proc Natl Acad Sci USA. 2008, 105, (38), 14288-92. Pubmed Link

 

"Codinaeopsin, an antimalarial fungal polyketide", Kontnik, R.; Clardy, J. Org Lett. 2008, 10, (18), 4149-51. Pubmed Link

 

"Sporulenes, heptaprenyl metabolites from Bacillus subtilis spores", Kontnik, R.; Bosak, T.; Butcher, R.A.; Brocks, J.J.; Losick, R.; Clardy, J.; Pearson, A. Org Lett. 2008, 10, (16), 3551-4. Pubmed Link

 

"Citral sensing by TRANSient receptor potential channels in dorsal root ganglion neurons", Stotz, S.C.; Vriens, J.; Martyn, D.; Clardy, J.; Clapham, D.E. PLoS ONE. 2008, 3, (5), e2082. Pubmed Link

 

"Development of a fluorescence polarization based assay for histone deacetylase ligand discovery", Mazitschek, R.; Patel, V.; Wirth, D.F.; Clardy, J. Bioorg Med Chem Lett. 2008, 18, (9), 2809-12. Pubmed Link

 

"The evolution of gene collectives: How natural selection drives chemical innovation", Fischbach, M. A.; Walsh, C. T.; Clardy, J. Proc. Natl. Acad. Sci. USA. 2008, 105, (12), 4601-8.  Pubmed Link

 

"Synthetic libraries of tyrosine-derived bacterial metabolites", Georgiades, S. N.; Clardy, J. Bioog Med Chem Lett. 2008, 18, (10), 3117-21. Pubmed Link

 

"Bombyx mori pheromone-binding protein binding nonpheromone ligands: implications for pheromone recognition", Lautenschlager, C.; Leal, W. S.; Clardy, J. Structure. 2007, 15, (9), 1148-54. PubMed Link

 

"Detecting binding interactions using microarrays of natural product extracts", Schmitz, K.; Haggarty, S. J.; McPherson, O. M.; Clardy, J.; Koehler, A. N. J. Am. Chem. Soc. 2007, 129, (37), 11346-7. PubMed Link

 

"High-throughput screens for small-molecule inhibitors of Pseudomonas aeruginosa biofilm development", Junker, L. M.; Clardy, J. Antimicrob Agents Chemother. 2007, 51, (10), 3582-90. PubMed Link

 

"Cyclic AMP directly activates NasP, an N-acyl amino acid antibiotic biosynthetic enzyme cloned from an uncultured beta-proteobacterium", Clardy, J.; Brady, S. F. J. Bacteriol. 2007, 189, (17), 6487-9. PubMed Link

 

"One pathway, many products", Fischbach, M. A.; Clardy, J. Nat Chem Biol. 2007, 3, (7), 353-5. Pubmed Link

 

"Small-molecule pheromones that control dauer development in Caenorhabditis elegans", Butcher, R. A.; Fujita, M.; Schroeder, F. C.; Clardy, J. Nat Chem Biol. 2007, 3, (7), 420-22. Pubmed Link

 

"Differential analysis of 2D NMR spectra: new natural products from a pilot-scale fungal extract library", Schroeder, F. C.; Gibson, D. M.; Churchill, A. C.; Sojikul, P.; Wursthorn, E. J.; Krasnoff, S. B.; Clardy, J. Angew. Chem. Int. Ed. Engl. 2007, 46, (6), 901-4. PubMed Link

 

"High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity", Martyn, D. C.; Jones, D. C.; Fairlamb, A. H.; Clardy, J. Bioorg. Med. Chem. Lett. 2007, 17, (5), 1280-3. PubMed Link

 

"The identification of bacillaene, the product of the PksX megacomplex in Bacillus subtilis", Butcher, R. A.; Schroeder, F. C.; Fischbach, M. A.; Straight, P. D.; Kolter, R.; Walsh, C. T.; Clardy, J. Proc. Natl. Acad. Sci. USA 2007, 104, (5), 1506-9. PubMed Link

 

"High-throughput Plasmodium falciparum growth assay for malaria drug discovery", Baniecki, M. L.; Wirth, D. F.; Clardy, J. Antimicrob. Agents Chemother. 2007, 51, (2), 716-23. PubMed Link

 

"FeeM, an N-acyl amino acid synthase from an uncultured soil microbe: structure, mechanism, and acyl carrier protein binding", Van Wagoner, R. M.; Clardy, J. Structure 2006, 14, (9), 1425-35. PubMed Link

 

"Isolation and structure assignment of an iminotetrasaccharide from a cultured filamentous cyanobacterium Anabaena sp.", Thammana, S.; Suzuki, H.; Lobkovsky, E.; Clardy, J.; Shimizu, Y. J. Nat. Prod. 2006, 69, (3), 365-8. PubMed Link

 

"Bisandrographolide from Andrographis paniculata activates TRPV4 channels", Smith, P. L.; Maloney, K. N.; Pothen, R. G.; Clardy, J.; Clapham, D. E. J. Biol. Chem. 2006, 281, (40), 29897-904. PubMed Link

 

"Differential Analysis of 2D NMR Spectra: New Natural Products from a Pilot-Scale Fungal Extract Library", Schroeder, F. C.; Gibson, D. M.; Churchill, A. C.; Sojikul, P.; Wursthorn, E. J.; Krasnoff, S. B.; Clardy, J. Angew. Chem. Int. Ed. Engl. 2006, 46, (6), 901-904. PubMed Link

 

"Phaeosphaeride A, an inhibitor of STAT3-dependent signaling isolated from an endophytic fungus", Maloney, K. N.; Hao, W.; Xu, J.; Gibbons, J.; Hucul, J.; Roll, D.; Brady, S. F.; Schroeder, F. C.; Clardy, J. Org. Lett. 2006, 8, (18), 4067-70. PubMed Link

 

"A biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid", Jin, M.; Fischbach, M. A.; Clardy, J. J. Am. Chem. Soc. 2006, 128, (33), 10660-1. PubMed Link

 

"Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators", Hieronymus, H.; Lamb, J.; Ross, K. N.; Peng, X. P.; Clement, C.; Rodina, A.; Nieto, M.; Du, J.; Stegmaier, K.; Raj, S. M.; Maloney, K. N.; Clardy, J.; Hahn, W. C.; Chiosis, G.; Golub, T. R. Cancer Cell 2006, 10, (4), 321-30. PubMed Link

 

"Preparation of a psammaplysene-based library", Georgiades, S. N.; Clardy, J. Org. Lett. 2006, 8, (19), 4251-4. PubMed Link

 

"New antibiotics from bacterial natural products", Clardy, J.; Fischbach, M. A.; Walsh, C. T. Nat. Biotechnol. 2006, 24, (12), 1541-50. PubMed Link

 

"Stopping trouble before it starts", Clardy, J. ACS Chem. Biol. 2006, 1, (1), 17-9. PubMed Link

 

"A chemical study of cyclic depsipeptides produced by a sponge-derived fungus", Amagata, T.; Morinaka, B. I.; Amagata, A.; Tenney, K.; Valeriote, F. A.; Lobkovsky, E.; Clardy, J.; Crews, P. J. Nat. Prod. 2006, 69, (11), 1560-5. PubMed Link

 

"Human methionine aminopeptidase type 2 in complex with l- and d-methionine", Nonato, M.; Widom, J.; Clardy, J. Bioorg. Med. Chem. Lett. 2006, 16, 2580-2583. PubMed Link

 

"Structure of Plasmodium falciparum dihydroorotate dehydrogenase with a bound inhibitor," Hurt, D.; Widom, J.; Clardy, J. Acta Crystallogr. D. Biol. Crystallogr. 2006, 62, 312-323. PubMed Link

 

"Brequinar derivatives and species-specific drug design for dihydroorotate dehydrogenase", Hurt, D.; Sutton, A.; Clardy, J. Bioorg. Med. Chem. Lett. 2006, 16, 1610-1615. PubMed Link

 

"Bacterial printing press that regenerates its ink: contact-printing bacteria using hydrogel stamps", Weibel, D. B.; Lee, A.; Mayer, M.; Brady, S. F.; Bruzewicz, D.; Yang, J.; Diluzio, W. R.; Clardy, J.; Whitesides, G. M. Langmuir 2005, 21, (14), 6436-42. PubMed Link

 

"Systematic Investigation of the Escherichia coli Metabolome for the Biosynthetic Origin of an Isocyanide Carbon Atom”, Brady, S.; Clardy, J. Angew. Chem. Int. Ed. Engl. 2005, 44, 7045-7048.  PubMed Link

 

"Coil-to-helix transition and ligand release of Bombyx mori pheromone-binding protein", Lautenschlager, C.; Leal, W.; Clardy, J. Biochem. Biophys. Res. Commun. 2005, 335, 1044-1050. PubMed Link

 

"Cloning and Heterologous Expression of Isocyanide Biosynthetic Genes from Environmental DNA", Brady, S.; Clardy, J. Angew. Chem. Int. Ed. Engl. 2005, 44, 7063-7065 PubMed Link

 

"Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export", Georgiades, S.; Clardy, J. Org. Lett. 2005, 7, 4091-4094. PubMed Link

 

"N-acyl derivatives of arginine and tryptophan isolated from environmental DNA expressed in Escherichia coli", Brady, S.; Clardy, J. Org. Lett. 2005, 7, 3613-3616. PubMed Link

 

"The psammaplysenes, specific inhibitors of FOXO1a nuclear export", Schroeder, F.; Kau, T.; Silver, P.; Clardy, J. J. Nat. Prod. 2005, 68, 574-576. PubMed Link

 

"Using genomics to deliver natural products from symbiotic bacteria", Clardy, J. Genome Biol. 2005, 6, 232. PubMed Link

 

"Lessons from natural molecules", Clardy, J.; Walsh, C. Nature 2004, 432, 829-837. PubMed Link

 

"Berkeleydione and berkeleytrione, new bioactive metabolites from an acid mine organism", Stierle, D. B.; Stierle, A. A.; Hobbs, J. D.; Stokken, J.; Clardy, J. Org Lett 2004, 6, (6), 1049-52. PubMed Link

 

"A further study of the cytotoxic constituents of a milnamide-producing sponge", Sonnenschein, R. N.; Farias, J. J.; Tenney, K.; Mooberry, S. L.; Lobkovsky, E.; Clardy, J.; Crews, P. Org Lett 2004, 6, (5), 779-82. PubMed Link

 

"Long-chain N-acyltyrosine synthases from environmental DNA", Brady, S.; Chao, C.; Clardy, J. Appl. Environ. Microbiol. 2004, 70, 6865-6870. PubMed Link

 

"Palmitoylputrescine, an Antibiotic Isolated from the Heterologous Expression of DNA Extracted from Bromeliad Tank Water", Brady, S. F.; Clardy, J. J. Nat. Prod. 2004, 67, 1283-1286. PubMed Link

"Tyrosol is a quorum-sensing molecule in Candida albicans", Chen, H.; Fujita, M.; Feng, Q.; Clardy, J.; Fink, G.R. Proc. Natl. Acad. Sci. USA 2004, 101, 5048-5052. PubMed Link

"A chemical genetic screen identified inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells", Kau, T.R.; Schroeder, F.; Ramaswamy, S.; Wojciechowski, C.L.; Zhao, J.J.; Roberts, T.M.; Clardy, J.; Sellers, W.R.; Silver, P. Cancer Cell 2003, 4, 463-476. PubMed Link

 

"The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2", Calero, G.; Gupta, P.; Nonato, M.C.; Tandel, S.; Biehl, E.R.; Hofmann, S.L.; Clardy, J. J. Biol. Chem. 2003, 278, 37957-64. PubMed Link

 

"Structural and functional analysis of pantocin A: an antibiotic from Pantoea agglomerans discovered by heterologous expression of cloned genes", Jin, M.; Liu, L.; Wright, S.A.I.; Beer, S.V.; Clardy J. Angew. Chem. Int. Ed. 2003, 42, 2898-2901. PubMed Link

 

"The biosynthetic gene cluster of pantocin A provides insights into biosynthesis and a tool for screening", Jin, M.; Wright, S.A.I.; Beer, S.V.; Clardy J. Angew. Chem. Int. Ed. 2003, 42, 2902-2905. PubMed Link

 

"Structure of the large FK506-binding protein FKBP51, an Hsp90-binding protein and a component of steroid receptor complexes", Sinars C. R.; Cheung-Flynn J.; Rimerman R. A.; Scammell J. G.; Smith D. F.; Clardy J. Proc. Natl. Acad. Sci. USA 2003, 100, 868-873. PubMed Link

 

"Synthesis of long-chain fatty acid enol esters isolated from an environmental DNA clone", Brady, S. F.; Clardy J. Org. Lett. 2003, 5, 121-4. PubMed Link

 

"Structural basis of m7GpppG binding to the nuclear cap-binding protein complex", Calero, G.; Wilson, K. F.; Ly, T.; Rios-Steiner J. L.; Clardy, J. C.; Cerione, R. A. Nat. Struct. Biol. 2002, 9, 912-917. PubMed Link

 

"New natural product families from an environmental DNA (eDNA) gene cluster", Brady, S. F.; Chao, C. J.; Clardy, J. J. Am. Chem. Soc. 2002, 124, 9968-9969. PubMed Link

 

"Crystal structure of the N-terminal segment of human eukaryotic translation initiation factor 2alpha", Nonato, M. C.; Widom, J.; Clardy J. J. Biol. Chem. 2002, 277, 17057-17061. PubMed Link

 

"Structural basis for the guanine nucleotide-binding activity of tissue transglutaminase and its regulation of transamidation activity", Liu, S.; Cerione, R. A.; Clardy, J. Proc. Natl. Acad. Sci USA 2002, 99, 2743-2747. PubMed Link

 

"Akanthomycin, a new antibiotic pyridone from the entomopathogenic fungus Akanthomyces gracillis", Wagenaar, M. M.; Gibson, D. M.; Clardy, J. Org. Lett. 2002, 4, 671-673. PubMed Link

 

"Synthesis and biological evaluation of analogues of the antibiotic pantocin B", Sutton, A. E.; Clardy, J. J. Am. Chem. Soc. 2001, 123, 9935-9446. PubMed Link

 

"The guanacastepenes: a highly diverse family of secondary metabolites produced by an endophytic fungus", Brady, S. F.; Bondi, S. M.; Clardy, J. J. Am. Chem. Soc. 2001, 123, 9900-9901. PubMed Link

 

"Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA", Brady, S. F.; Chao, C. J.; Handelsman, J.; Clardy, J. Org. Lett. 2001, 3, 1981-1984. PubMed Link

 

"Dicerandrols, new antibiotic and cytotoxic dimers producted by the fungus Phomopsis logicolla isolated from an endangered mint", Wagenaar, M. M.; Clardy, J. J. Nat. Prod. 2001, 64, 1006-1009. PubMed Link

 

"Two new roridins isolated from Myrothecium sp.", Wagenaar, M. M.; Clardy, J. J. Antibiotics 2001, 6, 517-520. PubMed Link

 

"The synthesis of potentially selective inhibitors of dihydroorotate dehydrogenase. The utilization of chemoselective Suzuki cross-coupling reactions in parallel synthesis", Sutton, A. E.; Clardy, J. Tetrahedron Lett. 2001, 42, 547-552.

 

"Long-chain N-Acyl amino acid antibiotics isolated from heterologously expressed environmental DNA", Brady, S. F.; Clardy, J. J. Am. Chem. Soc. 2000, 122, 12903-12904.

 

"CR377, a new pentaketide antifungal agent isolated from an endophytic fungus", Brady, S. F.; Clardy, J. J. Nat. Prod. 2000, 63, 1447-1448. PubMed Link

 

"The cytosporones, new octaketide antibiotics isolated from an endophytic fungus", Brady, S. F.; Wagenaar, M. M.; Singh, M. P.; Janso, J. E.; Clardy, J. Org. Lett. 2000, 2, 4043-4046. PubMed Link

 

"Cytoskyrins A and B, new BIA active bisanthraquinones isolated from an endophytic fungus", Brady, S. F.; Singh, M. P.; Janso, J. E.; Clardy, J. Org. Lett. 2000, 2, 4047-4049. PubMed Link

 

"Structural basis for the insensitivity of a serine enzyme (palmitoyl-protein thioesterase) to phenylmethylsulfonyl fluoride", Das, A. K.; Bellizzi, J. J.; Tandel, S.; Biehl, E.; Clardy, J.; Hofmann, S. L. J. Biol. Chem. 2000, 275, 23487-23851. PubMed Link

 

"Biological activity of guanacastepene, a novel diterpenoid antibiotic produced by an unidentified fungus CR115", Singh, M. P.; Janso, J. E.; Luckman, S. W.; Brady, S. F.; Clardy, J.; Greenstein, M.; Maiese, W. M. J. Antibiotics 2000, 53, 256-261. PubMed Link

 

"The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis", Bellizzi, J. J. III; Widom, J.; Kemp, C.; Lu, J. Y.; Das, A. K.; Hofmann, S. L.; Clardy, J. Proc. Nat. Acad. Sci. 2000, 97, 4573-4578. PubMed Link

 

"Guanacastepene, a fungal-derived diterpene antibiotic with a new carbon skeleton", Brady, S. F.; Singh, M.; Janso, J.; Clardy, J. J. Am. Chem. Soc. 2000, 122, 2116-2117.

 

"Sexual attraction in the silkworm moth: structure of the pheromone-binding-protein-bombykol complex", Sandler, B. H.; Nikonova, L.; Leal, W. S.; Clardy, J. Chem. Biol. 2000, 7, 143-151. PubMed Link

 

"Structure of human dihydroorotate dehydrogenase in complex with antiproliferative agents", Liu, S.; Neidhardt, E. A.; Grossman, T. H.; Ocain, T.; Clardy, J. Structure 2000, 8, 25-35. PubMed Link

 

"The total synthesis of Pantocin B", Sutton, A. E.; Clardy, J. Org. Lett. 2000, 2, 319-321. PubMed Link

 

"Pantocin B, an antibiotic from Erwinia herbicola discovered by heterologous expression of cloned genes", Brady, S. F.; Wright, S. A.; Lee, J. C.; Sutton, A. E.; Zumoff, C. H.; Wodzinski, R. S.; Beer, S. V.; & Clardy, J. J. Am. Chem. Soc. 1999, 121, 11912-11913.